Bioinformatician neoantigen peptide-based cancer vaccines

Bioinformatician neoantigen peptide-based cancer vaccines

Bioinformatician neoantigen peptide-based cancer vaccines
Join our team in developing personalised cancer vaccines for the treatment of pancreatic cancer
Closing date 18-11-2026

Closing date 18-11-2026

Within the Department of Pulmonary Medicine, we are seeking a highly motivated and enthusiastic bioinformatician who will join us in developing neoantigen peptide-based cancer vaccines for the treatment of pancreatic cancer patients.

Your main tasks will include

Develop and maintain a bioinformatics pipeline for neoantigen identification.
Analyze next-generation sequencing data (WES, RNA-seq) to identify tumor-specific mutations.
Implement and optimize machine learning algorithms for neoantigen prediction.
Integrate public and proprietary datasets to improve pipeline accuracy.
Collaborate with wet-lab scientists to validate predicted neoantigens.
Maintain and document computational workflows to ensure reproducibility.
Contribute to research publications and grant applications.

For candidates interested in pursuing a PhD, this position may provide an opportunity to develop into a PhD trajectory, depending on the candidate’s ambitions and performance, project progress, and funding availability.
The Neoantigen Peptide group is part of the Solid Tumor Immunology Research Rotterdam (STIRR) group at the Department of Pulmonary Medicine. The STIRR performs fundamental, translational, and clinical research to unravel the prerequisites for effective anti-tumor immunity and the mechanisms behind resistance to immunotherapies. Our research focuses on various types of cancer, including lung cancer, mesothelioma, pancreatic cancer, and melanoma.
The Neoantigen Peptide group develops novel neoantigen peptide-based cancer vaccines for the treatment of pancreatic cancer, a highly lethal neoplasm with a poor 5-year survival rate of